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Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway

Tracheal occlusion during lung development accelerates growth in response to increased intraluminal pressure. In order to investigate the role of internal pressure on murine early lung development, we cauterized the tip of the trachea, to occlude it, and thus to increase internal pressure. This meth...

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Autors principals: UNBEKANDT, MATHIEU, DEL MORAL, PIERRE MARIE, SALA, FREDERIC, BELLUSCI, SAVERIO, WARBURTON, DAVID, FLEURY, VINCENT
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275719/
https://ncbi.nlm.nih.gov/pubmed/18082381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2007.10.013
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