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Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway

Tracheal occlusion during lung development accelerates growth in response to increased intraluminal pressure. In order to investigate the role of internal pressure on murine early lung development, we cauterized the tip of the trachea, to occlude it, and thus to increase internal pressure. This meth...

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Detalhes bibliográficos
Main Authors: UNBEKANDT, MATHIEU, DEL MORAL, PIERRE MARIE, SALA, FREDERIC, BELLUSCI, SAVERIO, WARBURTON, DAVID, FLEURY, VINCENT
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275719/
https://ncbi.nlm.nih.gov/pubmed/18082381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2007.10.013
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