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FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis

BACKGROUND: Analyses of Fgf10 and Fgfr2b mutant mice, as well as human studies, suggest that FGF10/FGFR2b signaling may play an essential, nonredundant role during embryonic SMG development. To address this question, we have analyzed the SMG phenotype in Fgf10 and Fgfr2b heterozygous and null mutant...

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Detalhes bibliográficos
Main Authors: Jaskoll, Tina, Abichaker, George, Witcher, Daniel, Sala, Frederic G, Bellusci, Saverio, Hajihosseini, Mohammad K, Melnick, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184065/
https://ncbi.nlm.nih.gov/pubmed/15972105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-5-11
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