Fgf10/Fgfr2b Signaling in Mammary Gland Development, Homeostasis, and Cancer

Fibroblast growth factor 10 (Fgf10) is a secreted ligand acting via the Fibroblast growth factor receptor 2b (Fgfr2b). Fgf10/Fgfr2b signaling plays important roles both in the epithelium and in the mesenchyme during mammary gland development. Evidence in mice show that Fgf10 is critical for the indu...

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Main Authors: Stefano Rivetti, Chaolei Chen, Chengshui Chen, Saverio Bellusci
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-06-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
Fgf10
Fgfr2b
mammary gland
development
stem cells
cancer
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcell.2020.00415/full
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