Biomarker-based adaptive trials for patients with glioblastoma—lessons from I-SPY 2

The traditional clinical trials infrastructure may not be ideally suited to evaluate the numerous therapeutic hypotheses that result from the increasing number of available targeted agents combined with the various methodologies to molecularly subclassify patients with glioblastoma. Additionally, re...

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Bibliografske podrobnosti
Main Authors: Alexander, Brian M., Wen, Patrick Y., Trippa, Lorenzo, Reardon, David A., Yung, Wai-Kwan Alfred, Parmigiani, Giovanni, Berry, Donald A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714161/
https://ncbi.nlm.nih.gov/pubmed/23857706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not088
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