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Biomarker-based adaptive trials for patients with glioblastoma—lessons from I-SPY 2

The traditional clinical trials infrastructure may not be ideally suited to evaluate the numerous therapeutic hypotheses that result from the increasing number of available targeted agents combined with the various methodologies to molecularly subclassify patients with glioblastoma. Additionally, re...

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Detalhes bibliográficos
Main Authors: Alexander, Brian M., Wen, Patrick Y., Trippa, Lorenzo, Reardon, David A., Yung, Wai-Kwan Alfred, Parmigiani, Giovanni, Berry, Donald A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714161/
https://ncbi.nlm.nih.gov/pubmed/23857706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not088
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