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Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.

Cytotoxic activated macrophages (CM) inhibited the growth of neoplastic L1210 cells in vitro but L1210 cell death was minimal to nonexistent. L1210 cells injured by CM were separated from macrophages and studied in an isolated system. CM-injured L1210 cells had an absolute requirement for glucose or...

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Pubblicato in:J Clin Invest
Autori principali: Granger, D L, Taintor, R R, Cook, J L, Hibbs, J B
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371374/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7356685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109679
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