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Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.

Cytotoxic activated macrophages (CM) inhibited the growth of neoplastic L1210 cells in vitro but L1210 cell death was minimal to nonexistent. L1210 cells injured by CM were separated from macrophages and studied in an isolated system. CM-injured L1210 cells had an absolute requirement for glucose or...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Granger, D L, Taintor, R R, Cook, J L, Hibbs, J B
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1980
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371374/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7356685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109679
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