β-Chemokines Enhance Parasite Uptake and Promote Nitric Oxide-Dependent Microbiostatic Activity in Murine Inflammatory Macrophages Infected with Trypanosoma cruzi

In the present study, we describe the ability of Trypanosoma cruzi trypomastigotes to stimulate the synthesis of β-chemokines by macrophages. In vivo infection with T. cruzi led to MIP-1α, RANTES, and JE/MCP1 mRNA expression by cells from peritoneal inflammatory exudate. In addition, in vitro infect...

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Detalhes bibliográficos
Main Authors: Aliberti, Júlio C. S., Machado, Fabiana S., Souto, Janeusa T., Campanelli, Ana P., Teixeira, Mauro M., Gazzinelli, Ricardo T., Silva, João S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96814/
https://ncbi.nlm.nih.gov/pubmed/10456936
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