The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats

The present study sought to determine whether the combination of late preconditioning (PC) with postconditioning enhances the reduction in infarct size. Chronically instrumented rats were assigned to a 45-min (subset 1) or 60-min (subset 2) coronary occlusion followed by 24 h of reperfusion. In each...

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Bibliographic Details
Main Authors: Sato, Hiroshi, Bolli, Roberto, Rokosh, Gregg D., Bi, Qiuli, Dai, Shujing, Shirk, Gregg, Tang, Xian-Liang
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713472/
https://ncbi.nlm.nih.gov/pubmed/17704286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00858.2007
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