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MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration
Regulated gene expression determines the intrinsic ability of neurons to extend axons, and loss of such ability is the major reason for the failed axon regeneration in the mature mammalian CNS. MicroRNAs and histone modifications are key epigenetic regulators of gene expression, but their roles in m...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3713428/ https://ncbi.nlm.nih.gov/pubmed/23796896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.209619.112 |
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