MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration

Regulated gene expression determines the intrinsic ability of neurons to extend axons, and loss of such ability is the major reason for the failed axon regeneration in the mature mammalian CNS. MicroRNAs and histone modifications are key epigenetic regulators of gene expression, but their roles in m...

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Dettagli Bibliografici
Autori principali: Liu, Chang-Mei, Wang, Rui-Ying, Saijilafu, Jiao, Zhong-Xian, Zhang, Bo-Yin, Zhou, Feng-Quan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713428/
https://ncbi.nlm.nih.gov/pubmed/23796896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.209619.112
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