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Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration

Inactivation of glycogen synthase kinase 3 (GSK3) has been shown to mediate axon growth during development and regeneration. Phosphorylation of GSK3 by the kinase Akt is well known to be the major mechanism by which GSK3 is inactivated. However, whether such regulatory mechanism of GSK3 inactivation...

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Detalhes bibliográficos
Main Authors: Zhang, Bo-Yin, Saijilafu, Liu, Chang-Mei, Wang, Rui-Ying, Zhu, Qingsan, Jiao, Zhongxian, Zhou, Feng-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916952/
https://ncbi.nlm.nih.gov/pubmed/24333443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.12.037
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