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Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration

Inactivation of glycogen synthase kinase 3 (GSK3) has been shown to mediate axon growth during development and regeneration. Phosphorylation of GSK3 by the kinase Akt is well known to be the major mechanism by which GSK3 is inactivated. However, whether such regulatory mechanism of GSK3 inactivation...

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Dettagli Bibliografici
Autori principali: Zhang, Bo-Yin, Saijilafu, Liu, Chang-Mei, Wang, Rui-Ying, Zhu, Qingsan, Jiao, Zhongxian, Zhou, Feng-Quan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916952/
https://ncbi.nlm.nih.gov/pubmed/24333443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.12.037
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