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Mapping Small DNA Ligand Hydroxyl Radical Footprinting and Affinity Cleavage Products for Capillary Electrophoresis

The mapping of DNA footprints and affinity cleavage sites for small DNA ligands is affected by the choice of sequencing chemistry and end label, and the potential for indexing errors can be significant when mapping small ligand-DNA interactions. Described here is a mechanism for avoiding such errors...

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Detalhes bibliográficos
Main Authors: He, Gaofei, Vasilieva, Elena, Bashkin, James K., Dupureur, Cynthia M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713177/
https://ncbi.nlm.nih.gov/pubmed/23608054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.04.011
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