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Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early stage ethanol-mediated steatosis

OBJECTIVE: To examine the interaction of moderate and high dietary fat and ethanol with respect to formation of steatosis and regulation of the AMP-activated protein kinase (AMPK) pathway in a mouse model of chronic ethanol consumption. METHODS: Male C57BL/6J mice were pair-fed a modified Lieber-DeC...

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Detalhes bibliográficos
Main Authors: Shearn, Colin T., Smathers, Rebecca L., Jiang, Hua, Orlicky, David J., Maclean, Kenneth N., Petersen, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713161/
https://ncbi.nlm.nih.gov/pubmed/23465594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2012.12.002
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