Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships

The cross-recognition of peptides by cytotoxic T lymphocytes is a key element in immunology and in particular in peptide based immunotherapy. Here we develop three-dimensional (3D) quantitative structure-activity relationships (QSARs) to predict cross-recognition by Melan-A-specific cytotoxic T lymp...

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Detalhes bibliográficos
Main Authors: Fagerberg, Theres, Zoete, Vincent, Viatte, Sebastien, Baumgaertner, Petra, Alves, Pedro M., Romero, Pedro, Speiser, Daniel E., Michielin, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713012/
https://ncbi.nlm.nih.gov/pubmed/23874382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065590
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