Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients

Enhancing immune responses with immune-modulatory monoclonal antibodies directed to inhibitory immune receptors is a promising modality in cancer therapy. Clinical efficacy has been demonstrated with antibodies blocking inhibitory immune checkpoints such as cytotoxic T lymphocyte–associated antigen...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Romano, Emanuela, Kusio-Kobialka, Monika, Foukas, Periklis G., Baumgaertner, Petra, Meyer, Christiane, Ballabeni, Pierluigi, Michielin, Olivier, Weide, Benjamin, Romero, Pedro, Speiser, Daniel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434760/
https://ncbi.nlm.nih.gov/pubmed/25918390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417320112
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