Purinogenic Immunodeficiency Diseases: DIFFERENTIAL EFFECTS OF DEOXYADENOSINE AND DEOXYGUANOSINE ON DNA SYNTHESIS IN HUMAN T LYMPHOBLASTS

Deoxyadenosine and deoxyguanosine are toxic to human lymphoid cells in culture and have been implicated in the pathogenesis of the immunodeficiency states associated with adenosine deaminase and purine nucleoside phosphorylase deficiency, respectively. We have studied the relative incorporation of s...

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Autores principales: Wilson, James M., Mitchell, Beverly S., Daddona, Peter E., Kelley, William N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1979
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC371297/
https://ncbi.nlm.nih.gov/pubmed/115901
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