Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

Animal studies generate valuable hypotheses that lead to the conduct of preventive or therapeutic clinical trials. We assessed whether there is evidence for excess statistical significance in results of animal studies on neurological disorders, suggesting biases. We used data from meta-analyses of i...

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Bibliografski detalji
Glavni autori: Tsilidis, Konstantinos K., Panagiotou, Orestis A., Sena, Emily S., Aretouli, Eleni, Evangelou, Evangelos, Howells, David W., Salman, Rustam Al-Shahi, Macleod, Malcolm R., Ioannidis, John P. A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712913/
https://ncbi.nlm.nih.gov/pubmed/23874156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001609
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