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Genome-wide Significant Associations for Variants With Minor Allele Frequency of 5% or Less—An Overview: A HuGE Review

The authors survey uncommon variants (minor allele frequency, ≤5%) that have reached genome-wide significance (P ≤ 10(−7)) in genome-wide association study(ies) (GWAS). They examine the typical effect sizes of these associations; whether they have arisen in multiple GWAS on the same phenotype; and w...

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Detalhes bibliográficos
Publicado no:Am J Epidemiol
Main Authors: Panagiotou, Orestis A., Evangelou, Evangelos, Ioannidis, John P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719165/
https://ncbi.nlm.nih.gov/pubmed/20876667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwq234
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