NQO1 Polymorphisms and De Novo Childhood Leukemia: A HuGE Review and Meta-Analysis

Polymorphisms in NQO1, a gene coding for the phase II enzyme involved in the detoxification of quinone carcinogens, have been associated with childhood leukemia in some studies, although the observed direction and magnitude of effects have been inconsistent. Therefore, the authors systematically rev...

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Main Authors: Guha, Neela, Chang, Jeffrey S., Chokkalingam, Anand P., Wiemels, Joseph L., Smith, Martyn T., Buffler, Patricia A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727266/
https://ncbi.nlm.nih.gov/pubmed/18945694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwn246
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