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Effect of Cytochrome P450 3A5 Genotype on Atorvastatin Pharmacokinetics and Its Interaction with Clarithromycin
STUDY OBJECTIVE: To assess the effects of the cytochrome P450 (CYP) 3A genotype, CYP3A5, on atorvastatin pharmacokinetics and its interaction with clarithromycin. DESIGN: Prospective, two-phase, randomized-sequence, open-label pharmacokinetic study. SETTING: Clinical research center at a teaching ho...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712822/ https://ncbi.nlm.nih.gov/pubmed/21950641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1592/phco.31.10.942 |
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