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Methods of utilizing baseline values for indirect response models

This study derives and assesses modified equations for Indirect Response Models (IDR) for normalizing data for baseline values (R(0)) and evaluates different methods of utilizing baseline information. Pharmacodynamic response equations for the four basic IDR models were adjusted to reflect a ratio t...

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Bibliographic Details
Main Authors: Woo, Sukyung, Pawaskar, Dipti, Jusko, William J.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712653/
https://ncbi.nlm.nih.gov/pubmed/19697107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-009-9128-6
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