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Methods of utilizing baseline values for indirect response models
This study derives and assesses modified equations for Indirect Response Models (IDR) for normalizing data for baseline values (R(0)) and evaluates different methods of utilizing baseline information. Pharmacodynamic response equations for the four basic IDR models were adjusted to reflect a ratio t...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712653/ https://ncbi.nlm.nih.gov/pubmed/19697107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-009-9128-6 |
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