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Characteristics of indirect pharmacodynamic models and applications to clinical drug responses
This review describes four basic physiologic indirect pharmacodynamic response (IDR) models which have been proposed to characterize the pharmacodynamics of drugs that act by indirect mechanisms such as inhibition or stimulation of the production or dissipation of factors controlling the measured ef...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1873365/ https://ncbi.nlm.nih.gov/pubmed/9517366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00676.x |
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