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Markers of resistance to anti-EGFR therapy in colorectal cancer

Epidermal growth factor receptor (EGFR) is a therapeutic target in colorectal cancer (CRC). The benefit from EGFR inhibitors appears to be limited to a subset of patients with CRC. Mechanisms of resistance to EGFR inhibitors are being identified. KRAS codon 12 activating mutation is a predominate me...

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Библиографические подробности
Главные авторы: Shaib, Walid, Mahajan, Reena, El-Rayes, Bassel
Формат: Artigo
Язык:Inglês
Опубликовано: Pioneer Bioscience Publishing Company 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712296/
https://ncbi.nlm.nih.gov/pubmed/23997942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2013.029
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