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Mechanisms of resistance to anti-EGFR therapy in colorectal cancer

Targeting the epidermal growth factor receptor (EGFR) either alone or in combination with chemotherapy is effective for patients with RAS wild type metastatic colorectal cancer (mCRC). However, only a small percentage of mCRC patients are sensitive to anti-EGFR therapy and even the best cases finall...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhao, Ben, Wang, Lu, Qiu, Hong, Zhang, Mingsheng, Sun, Li, Peng, Ping, Yu, Qianqian, Yuan, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354808/
https://ncbi.nlm.nih.gov/pubmed/28002810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14012
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