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Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance

Cetuximab and panitumumab, as the highly effective antibodies targeting epidermal growth factor receptor (EGFR), have clinical activity in the patients with metastatic colorectal cancer (mCRC). These agents have good curative efficacy, but drug resistance also exists at the same time. The effects of...

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Detalhes bibliográficos
Publicado no:Gastroenterol Rep (Oxf)
Main Authors: Li, Qing-Hai, Wang, Ying-Zhao, Tu, Jian, Liu, Chu-Wei, Yuan, Yu-Jie, Lin, Run, He, Wei-Ling, Cai, Shi-Rong, He, Yu-Long, Ye, Jin-Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7333932/
https://ncbi.nlm.nih.gov/pubmed/32665850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gastro/goaa026
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