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Pharmacodynamics of Glucose Regulation by Methylprednisolone. II. Normal Rats
A physiologic pharmacodynamic model was developed to jointly describe the effects of methylprednisolone (MPL) on adrenal suppression and glycemic control in normal rats. Six groups of animals were given MPL intravenously at 0, 10 and 50 mg/kg, or by subcutaneous 7 day infusion at rates of 0, 0.1 and...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712293/ https://ncbi.nlm.nih.gov/pubmed/19156669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.642 |
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