Pharmacodynamic Modeling of Acute and Chronic Effects of Methylprednisolone on Hepatic Urea Cycle Genes in Rats

Corticosteroids (CS) regulate many enzymes at both mRNA and protein levels. This study used microarrays to broadly assess regulation of various genes related to the greater urea cycle and employs pharmacokinetic/pharmacodynamic (PK/PD) modeling to quantitatively analyze and compare the temporal prof...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hazra, Anasuya, DuBois, Debra C., Almon, Richard R., Snyder, Grayson H., Jusko, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2008
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733100/
https://ncbi.nlm.nih.gov/pubmed/19787073
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados