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Modeling of Corticosteroid Effects on Hepatic Low-Density Lipoprotein Receptors and Plasma Lipid Dynamics in Rats

PURPOSE: This study examines methylprednisolone (MPL) effects on the dynamics of hepatic low-density lipoprotein receptor (LDLR) mRNA and plasma lipids associated with increased risks for atherosclerosis. MATERIALS AND METHODS: Normal male Wistar rats were given 50 mg/kg MPL intramuscularly (IM) and...

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Detalhes bibliográficos
Main Authors: Hazra, Anasuya, Pyszczynski, Nancy A., DuBois, Debra C., Almon, Richard R., Jusko, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196440/
https://ncbi.nlm.nih.gov/pubmed/17674160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-007-9371-8
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