Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease

Behavioural assays represent sensitive methods for detecting neuronal dysfunction in model organisms. A number of manual methods have been established for Drosophila, however these are time-consuming and generate parameter-poor phenotype descriptors. Here, we have developed an automated computer vis...

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Detalhes bibliográficos
Main Authors: Jahn, Thomas R., Kohlhoff, Kai J., Scott, Michael, Tartaglia, Gian Gaetano, Lomas, David A., Dobson, Christopher M., Vendruscolo, Michele, Crowther, Damian C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2011
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712187/
https://ncbi.nlm.nih.gov/pubmed/21315762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2011.01.026
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