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X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell Function
Patients with type 2 diabetes (T2D) often exhibit hyperglucagonemia despite hyperglycemia, implicating defective α-cell function. Although endoplasmic reticulum (ER) stress has been suggested to underlie β-cell dysfunction in T2D, its role in α-cell biology remains unclear. X-box binding protein 1 (...
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Huvudupphovsmän: | , , , , , , , |
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Materialtyp: | Artigo |
Språk: | Inglês |
Publicerad: |
American Diabetes Association
2013
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Ämnen: | |
Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712068/ https://ncbi.nlm.nih.gov/pubmed/23493568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1747 |
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