X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell Function

Patients with type 2 diabetes (T2D) often exhibit hyperglucagonemia despite hyperglycemia, implicating defective α-cell function. Although endoplasmic reticulum (ER) stress has been suggested to underlie β-cell dysfunction in T2D, its role in α-cell biology remains unclear. X-box binding protein 1 (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Akiyama, Masaru, Liew, Chong Wee, Lu, Shusheng, Hu, Jiang, Martinez, Rachael, Hambro, Ben, Kennedy, Robert T., Kulkarni, Rohit N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2013
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712068/
https://ncbi.nlm.nih.gov/pubmed/23493568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1747
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg