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Ku70 Functions in Addition to Nonhomologous End Joining in Pancreatic β-Cells: A Connection to β-Catenin Regulation

The genesis of β-cells predominantly occurs through self-replication; therefore, understanding the regulation of cell proliferation is essential. We previously showed that the lack of nonhomologous end joining (NHEJ) DNA repair factor ligase IV leads to an accumulation of DNA damage that permanently...

詳細記述

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書誌詳細
主要な著者: Tavana, Omid, Puebla-Osorio, Nahum, Kim, Jiseong, Sang, Mei, Jang, Stella, Zhu, Chengming
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712041/
https://ncbi.nlm.nih.gov/pubmed/23474484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1218
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