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A novel Ku70 function in colorectal homeostasis separate from nonhomologous end joining
Ku70, a known nonhomologous end-joining (NHEJ) factor, also functions in tumor suppression, although this molecular mechanism remains uncharacterized. Previously, we showed that mice deficient for DNA ligase IV (Lig4), another key NHEJ factor, succumbed to aggressive lymphoma in the absence of tumor...
שמור ב:
| הוצא לאור ב: | Oncogene |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761319/ https://ncbi.nlm.nih.gov/pubmed/23752193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.234 |
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