Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: A Revised Model of Human β-Cell G1/S Control

Harnessing control of human β-cell proliferation has proven frustratingly difficult. Most G1/S control molecules, generally presumed to be nuclear proteins in the human β-cell, are in fact constrained to the cytoplasm. Here, we asked whether G1/S molecules might traffic into and out of the cytoplasm...

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Detalhes bibliográficos
Main Authors: Fiaschi-Taesch, Nathalie M., Kleinberger, Jeffrey W., Salim, Fatimah G., Troxell, Ronnie, Wills, Rachel, Tanwir, Mansoor, Casinelli, Gabriella, Cox, Amy E., Takane, Karen K., Srinivas, Harish, Scott, Donald K., Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712040/
https://ncbi.nlm.nih.gov/pubmed/23493571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0778
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