Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: A Revised Model of Human β-Cell G1/S Control

Harnessing control of human β-cell proliferation has proven frustratingly difficult. Most G1/S control molecules, generally presumed to be nuclear proteins in the human β-cell, are in fact constrained to the cytoplasm. Here, we asked whether G1/S molecules might traffic into and out of the cytoplasm...

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Autors principals: Fiaschi-Taesch, Nathalie M., Kleinberger, Jeffrey W., Salim, Fatimah G., Troxell, Ronnie, Wills, Rachel, Tanwir, Mansoor, Casinelli, Gabriella, Cox, Amy E., Takane, Karen K., Srinivas, Harish, Scott, Donald K., Stewart, Andrew F.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712040/
https://ncbi.nlm.nih.gov/pubmed/23493571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0778
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