Synthesis and structure−activity relationship of 8-substituted protoberberine derivatives as a novel class of antitubercular agents

BACKGROUND: The emergence of multi-drug resistant tuberculosis (MDR-TB) has heightened the need for new chemical classes and innovative strategies to tackle TB infections. It is urgent to discover new classes of molecules without cross-resistance with currently used antimycobacterial drugs. RESULTS:...

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Main Authors: Li, Ying-Hong, Fu, Hai-Gen, Su, Feng, Gao, Li-Mei, Tang, Sheng, Bi, Chong-Wen, Li, Yu-Huan, Wang, Yan-Xiang, Song, Dan-Qing
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712002/
https://ncbi.nlm.nih.gov/pubmed/23837573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-117
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