Genetic Analysis of Synaptotagmin C2 Domain Specificity in Regulating Spontaneous and Evoked Neurotransmitter Release

Synaptic vesicle fusion mediates communication between neurons and is triggered by rapid influx of Ca(2+). The Ca(2+)-triggering step for fusion is regulated by the synaptic vesicle transmembrane protein Synaptotagmin 1 (Syt1). Syt1 contains two cytoplasmic C2 domains, termed C2A and C2B, which coor...

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Bibliografiske detaljer
Main Authors: Lee, Jihye, Guan, Zhuo, Akbergenova, Yulia, Littleton, J. Troy
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711629/
https://ncbi.nlm.nih.gov/pubmed/23283333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3214-12.2013
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