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Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1
Synaptic vesicle fusion at many synapses has been kinetically separated into two distinct Ca(2+)-dependent temporal components consisting of a rapid synchronous phase followed by a slower asynchronous component. Mutations in the synaptic vesicle Ca(2+) sensor Synaptotagmin 1 (Syt 1) reduce synchrono...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930414/ https://ncbi.nlm.nih.gov/pubmed/20679236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000606107 |
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