Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of Complexin

Complexins are small α-helical proteins that modulate neurotransmitter release by binding to SNARE complexes during synaptic vesicle exocytosis. They have been found to function as fusion clamps to inhibit spontaneous synaptic vesicle fusion in the absence of Ca(2+), while also promoting evoked neur...

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Bibliografiske detaljer
Main Authors: Buhl, Lauren K., Jorquera, Ramon A., Akbergenova, Yulia, Huntwork-Rodriguez, Sarah, Volfson, Dina, Littleton, J. Troy
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540146/
https://ncbi.nlm.nih.gov/pubmed/23159779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.11.009
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