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Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of Complexin

Complexins are small α-helical proteins that modulate neurotransmitter release by binding to SNARE complexes during synaptic vesicle exocytosis. They have been found to function as fusion clamps to inhibit spontaneous synaptic vesicle fusion in the absence of Ca(2+), while also promoting evoked neur...

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Detalhes bibliográficos
Main Authors: Buhl, Lauren K., Jorquera, Ramon A., Akbergenova, Yulia, Huntwork-Rodriguez, Sarah, Volfson, Dina, Littleton, J. Troy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540146/
https://ncbi.nlm.nih.gov/pubmed/23159779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.11.009
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