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Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of Complexin

Complexins are small α-helical proteins that modulate neurotransmitter release by binding to SNARE complexes during synaptic vesicle exocytosis. They have been found to function as fusion clamps to inhibit spontaneous synaptic vesicle fusion in the absence of Ca(2+), while also promoting evoked neur...

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Bibliografische gegevens
Hoofdauteurs: Buhl, Lauren K., Jorquera, Ramon A., Akbergenova, Yulia, Huntwork-Rodriguez, Sarah, Volfson, Dina, Littleton, J. Troy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540146/
https://ncbi.nlm.nih.gov/pubmed/23159779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.11.009
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