A Target Cell-Specific Role for Presynaptic Fmr1 in Regulating Glutamate Release onto Neocortical Fast-Spiking Inhibitory Neurons

In the mouse model of Fragile X syndrome, the Fmr1 knock-out, local excitation of layer 4 fast-spiking (FS) inhibitory neurons is robustly decreased by 50%, but the mechanisms mediating this change are unknown. Here, we performed recordings in acutely prepared slices obtained from Fmr1 “mosaic” mice...

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Detaylı Bibliyografya
Asıl Yazarlar: Patel, Ankur B., Hays, Seth A., Bureau, Ingrid, Huber, Kimberly M., Gibson, Jay R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2013
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711607/
https://ncbi.nlm.nih.gov/pubmed/23392687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2447-12.2013
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