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Altered Neocortical Rhythmic Activity States in Fmr1 KO Mice Are Due to Enhanced mGluR5 Signaling and Involve Changes in Excitatory Circuitry

Despite the pronounced neurological deficits associated with mental retardation and autism, the degree to which neocortical circuit function is altered remains unknown. Here, we study changes in neocortical network function in the form of persistent activity states in the mouse model of fragile X sy...

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Bibliographic Details
Main Authors: Hays, Seth A., Huber, Kimberly M., Gibson, Jay R.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207280/
https://ncbi.nlm.nih.gov/pubmed/21976507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3157-11.2011
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