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Altered Neocortical Rhythmic Activity States in Fmr1 KO Mice Are Due to Enhanced mGluR5 Signaling and Involve Changes in Excitatory Circuitry

Despite the pronounced neurological deficits associated with mental retardation and autism, the degree to which neocortical circuit function is altered remains unknown. Here, we study changes in neocortical network function in the form of persistent activity states in the mouse model of fragile X sy...

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Detalhes bibliográficos
Main Authors: Hays, Seth A., Huber, Kimberly M., Gibson, Jay R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207280/
https://ncbi.nlm.nih.gov/pubmed/21976507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3157-11.2011
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