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C-Reactive Protein and CFH, ARMS2/HTRA1 Gene Variants Are Independently Associated with Risk of Macular Degeneration

PURPOSE: Genetic variants CFH and ARMS2/HTRA1 gene regions as well as high-sensitivity C-reactive protein (CRP) levels are related to age-related macular degeneration (AMD). We evaluated their independent and combined effects on risk of AMD, as well as their interactions. DESIGN: Case-control study....

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Detalhes bibliográficos
Main Authors: Seddon, Johanna M., Gensler, Gary, Rosner, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711558/
https://ncbi.nlm.nih.gov/pubmed/20346514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ophtha.2009.11.020
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