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Three New Genetic Loci (R1210C in CFH, Variants in COL8A1 and RAD51B) Are Independently Related to Progression to Advanced Macular Degeneration

OBJECTIVES: To assess the independent impact of new genetic variants on conversion to advanced stages of AMD, controlling for established risk factors, and to determine the contribution of genes in predictive models. METHODS: In this prospective longitudinal study of 2765 individuals, 777 subjects p...

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Detalles Bibliográficos
Main Authors: Seddon, Johanna M., Reynolds, Robyn, Yu, Yi, Rosner, Bernard
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909074/
https://ncbi.nlm.nih.gov/pubmed/24498017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087047
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