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Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates

PURPOSE. To determine the association between genetic variants and transition to advanced age-related macular degeneration (AMD), and to develop a predictive model and online application to assist in clinical decision making. METHODS. Among 2951 subjects in the Age-Related Eye Disease Study, 834 pro...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Seddon, Johanna M., Silver, Rachel E., Kwong, Manlik, Rosner, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405097/
https://ncbi.nlm.nih.gov/pubmed/25655794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15841
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