Elevated TRF2 in advanced breast cancers with short telomeres

INTRODUCTION: Telomere repeat binding factor 2 (TRF2) binds directly to telomeres and preserves the structural integrity of chromosome ends. In vitro models suggest that expression of TRF2 protein increases during mammary cancer progression. However, a recent study has reported that TRF2 mRNA levels...

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Main Authors: Diehl, Malissa C., Idowu, Michael O., Kimmelshue, Katherine, York, Timothy P., Jackson-Cook, Colleen, Turner, Kristi, Holt, Shawn E., Elmore, Lynne W.
格式: Artigo
語言:Inglês
出版: 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711524/
https://ncbi.nlm.nih.gov/pubmed/20625812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-0988-7
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