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Live-Cell Imaging of Ubiquitin–Proteasome System Function

The role of the ubiquitin–proteasome system (UPS) in maintaining protein homeostasis has generated a demand for assays that quantify UPS function in the presence of chemical and protein UPS inhibitors. Here, we describe protocols that measure changes in UPS reporter levels in response to changes in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hipp, Mark S., Bersuker, Kirill, Kopito, Ron R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711503/
https://ncbi.nlm.nih.gov/pubmed/22350906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-474-2_33
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