4-Hydroxynonenal Induces G(2)/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway

4-Hydroxynonenal (HNE) has been widely implicated in the mechanisms of oxidant-induced toxicity, but the detrimental effects of HNE associated with DNA damage or cell cycle arrest have not been thoroughly studied. Here we demonstrate for the first time that HNE caused G(2)/M cell cycle arrest of hep...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Chaudhary, Pankaj, Sharma, Rajendra, Sahu, Mukesh, Vishwanatha, Jamboor K., Awasthi, Sanjay, Awasthi, Yogesh C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711318/
https://ncbi.nlm.nih.gov/pubmed/23733185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.467662
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller